- Anaphylaxis is a form of distributive shock that, in short, results from excessive vasodilation and impaired distribution of blood flow throughout the body. [17]
- Cardiac output (CO) and Systemic Vascular Resistance (SVR) are the determinants of tissue perfusion.
- Cardiac output = Heart Rate x Stroke Volume
- Systemic Vascular Resistance is dependent on the blood viscosity vessel length & diameter. [18]
- As we will discuss, during an anaphylactic reaction, cardiac output and systemic vascular resistance will be changed and, if left untreated, death ensues.
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