Aspirin

Ibuprofen and Interaction and use in Myocardial Infarction
  • Ibuprofen acts differently than aspirin
  • Ibuprofen acts on a different variation of cyclooxygenase
  • Aspirin blocks COX-1 as previously discussed
  • Suggested data also shows nonsteroidal medications (NSAIDS such as Motrin, Naprosyn) do NOT reduce the risk of myocardial infarction [20]
  • NSIADS bind reversibly at the active site of the enzyme, depressing platelet function only during the dosing schedule