Diseases of Concern Tuberculosis

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Pathophysiology Continued
  • During this process the body begins to send more cells to assist in the clean up process
  • Monocytes are attracted to the site but do not have the ability to kill the bacilli
  • The infected macrophage may be transported throughout the body through the lymphatic system
  • The areas that attract the macrophage with the bacilli are areas of high oxygen concentration, such as kidneys, bones, brain and apical portion of the lungs
  • This spread is usually asymptomatic but produces metastatic foci throughout the body which may become active at a later date
  • Most patients are able to produce an effective immune response
  • T lymphocytes are activated and are able to control the infection with in 2-10 weeks
  • The lymphocyte activation causes the patient to have a positive tuberculin skin test[5]

 


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