- There are four regimens outline for latent TB
- The medications used are as followed
- isoniazid (INH)
- rifampin (RIF)
- rifapentine (RPT)
The CDC outlines the following 4 regimins
Table 2. Latent TB Infection Treatment Regimens
|
Drugs |
Duration |
Interval |
Minimum doses |
|
Isoniazid |
9 months |
Daily |
270 |
|
Twice weekly* |
76
|
|
Isoniazid |
6 months |
Daily |
180 |
|
Twice weekly* |
52
|
|
Isoniazid & Rifapentine |
3 months |
Once weekly* |
12
|
|
Rifampin |
4 months |
Daily |
120
|
|
*Use Directly Observed Therapy (DOT). Note: Due to the reports of severe liver injury and deaths, CDC recommends that the combination of rifampin (RIF) and pyrazinamide (PZA) should generally not be offered for the treatment of latent TB infection. [5] |