Diseases of Concern Tuberculosis

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TB Disease Treatment
  • Treating TB disease differs from latent TB
  • Treatment is over 6-9 months
  • There are 10 medication approved for testament: below are the four first line medications
    1. isoniazid (INH)
    2. rifampin (RIF)
    3. ethambutol (EMB)
    4. pyrazinamide (PZA)

CDC outline regimens below

Preferred Regimen

Alternative Regimen

Alternative Regimen

Initial Phase
Daily INH, RIF, PZA, and EMB* for 56 doses (8 weeks)

Initial Phase
Daily INH, RIF, PZA, and EMB* for 14 doses (2 weeks), then twice weekly for 12 doses (6 weeks)

Initial Phase
Thrice-weekly INH, RIF, PZA, and EMB* for 24 doses (8 weeks)

Continuation Phase
Daily INH and RIF for 126 doses (18 weeks)
or
Twice-weekly INH and RIF for 36 doses (18 weeks)[5]

Continuation Phase
Twice-weekly INH and RIF for 36 doses (18 weeks)

Continuation Phase
Thrice-weekly INH and RIF for 54 doses (18 weeks)
  • Tuberculosis drug therapy has multiple side affects and drug interactions that should be carefully monitored by the patients provider
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