| Atherosclerotic plaque can build up in any or all of these coronary arteries. Blockage in any one of these main arteries or their branches results in myocardial cell death. This is the definition of myocardial infarction (a.k.a. the heart attack), an acute coronary syndrome. Depending on the vessels that are blocked, there will be different parts of the heart muscle affected and different clinical and ECG findings. | | | | | |