Toxicological Emergencies

GHB Composition
GHB comes as a tan or white powder, that is mixed in liquid to be taken as a drink.  The effect caused by GHB is usually one of sedation and release of inhibitions.  The release of inhibition, however, can cause a paradoxical agitation.  It is rapidly absorbed, and metabolizes quickly as well.  The clinical hallmark in acute overdose is a patient with coma who quickly becomes combative, especially during painful stimulation.