Allergic Reactions and Anaphylaxis

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Glucagon
  • Some studies have indicated that patients who are taking beta-blocking medications may be resistant to treatments with Epinephrine and Beta agonists.
  • Some patients have developed reflex bradycardia and hypotension.
  • In such cases, administration of Glucagon IVP should be administered.  This is because the inotropic and chronotropic effects that Glucagon IVP possesses are not mediated through beta-receptors.
  • Adult dose of 1 - 5mg IVP over five minutes.
  • Adverse reactions may include vomiting, so ensure a patent airway at all times. [14]
Refer to your local protocol for Glucagon administration for patients taking beta-blockers.
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